Cloning and characterization of the 5'-flanking region of the human growth hormone secretagogue receptor gene.

@article{Kaji1998CloningAC,
  title={Cloning and characterization of the 5'-flanking region of the human growth hormone secretagogue receptor gene.},
  author={Hiroshi Kaji and Sachiko Tai and Yasuhiko Okimura and Genzo Iguchi and Yutaka Takahashi and Hiroshi Abe and K unihiro Chihara},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 51},
  pages={
          33885-8
        }
}
Recently, the growth hormone secretagogue receptor (GHS-R) cDNA has been isolated from the pituitary and hypothalamus. To evaluate the regulation of human (h) GHS-R gene expression, we cloned the hGHS-R gene containing the 5'-flanking region of 0.6-2.9 kilobase pairs. Analysis of the hGHS-R transcripts with 5'-rapid amplification of cDNA ends suggested that the putative transcription initiation site was approximately -453 base pairs upstream of the translation initiation site (+1). There is no… CONTINUE READING
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