Corpus ID: 25342692

Cloning and characterization of integrin alpha subunits from the solitary ascidian, Halocynthia roretzi.

  title={Cloning and characterization of integrin alpha subunits from the solitary ascidian, Halocynthia roretzi.},
  author={Seita Miyazawa and Kaoru Azumi and Masaru Nonaka},
  journal={Journal of immunology},
  volume={166 3},
Recent molecular and biochemical analysis has revealed the presence of an opsonic complement system in the solitary ascidian, Halocynthia roretzi, composed of at least C3, two mannan binding protein-associated serine proteases, and factor B. To elucidate further the structure and function of this apparently primitive complement system in the urochordates, we looked for the ascidian complement receptor type 3 (CR3), or type 4 (CR4), which are members of the leukocyte integrin family in mammals… Expand
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