Cloning and characterization of human histone deacetylase 8.


To date, seven different human histone deacetylases (HDACs) have been identified, which fall into two distinct classes. We have isolated and characterized a cDNA encoding a novel human HDAC, which we name HDAC8. HDAC8 shows a high degree of sequence similarity to HDAC1 and HDAC2 and thus belongs to the class I of HDACs. HDAC8 is expressed in a variety of… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.