Cloning and characterization of hepaCAM, a novel Ig-like cell adhesion molecule suppressed in human hepatocellular carcinoma.

@article{ChungMoh2005CloningAC,
  title={Cloning and characterization of hepaCAM, a novel Ig-like cell adhesion molecule suppressed in human hepatocellular carcinoma.},
  author={Mei Chung Moh and Lay Hoon Lee and Shali Shen},
  journal={Journal of hepatology},
  year={2005},
  volume={42 6},
  pages={
          833-41
        }
}
BACKGROUND/AIMS Previously, we reported on gene HEPN1 that was silenced in hepatocellular carcinoma (HCC) and its capability of arresting cell growth. In this study, we identified another novel gene hepaCAM from the liver, which contains the full-length HEPN1 on its antisense strand in the 3'-noncoding region, and assessed its expression, characteristics and functions in HCC. METHODS Full-length hepaCAM cDNA was isolated by rapid amplification of cDNA ends. The gene expression was examined by… Expand
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