Cloning and characterization of guanine deaminase from mouse and rat brain.

@article{Paletzki2002CloningAC,
  title={Cloning and characterization of guanine deaminase from mouse and rat brain.},
  author={Ronald F. Paletzki},
  journal={Neuroscience},
  year={2002},
  volume={109 1},
  pages={15-26}
}
A search for genes differentially expressed in the rat striatum revealed a gene fragment with a ventral to dorsal striatal expression pattern. The sequence of the fragment was used to isolate mouse and rat clones that upon sequencing were identified as homologous to human guanine deaminase. Here we report the distribution of guanine deaminase in the rodent brain. In situ hybridization localization of the encoding mRNA showed a distribution primarily in forebrain areas including cortical… CONTINUE READING

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