Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family.

@article{Cribbs1998CloningAC,
  title={Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family.},
  author={Leanne L. Cribbs and Jin Hee Lee and J Yang and Jonathan Satin and Yan Jessie Zhang and Asif N Daud and Jane Barclay and Magali P. Williamson and Mark H Fox and Michele Rees and Edward Perez-Reyes},
  journal={Circulation research},
  year={1998},
  volume={83 1},
  pages={103-9}
}
Voltage-activated Ca2+ channels exist as multigene families that share common structural features. Different Ca2+ channels are distinguished by their electrophysiology and pharmacology and can be classified as either low or high voltage-activated channels. Six alpha1 subunit genes cloned previously code for high voltage-activated Ca2+ channels; therefore, we have used a database search strategy to identify new Ca2+ channel genes, possibly including low voltage-activated (T-type) channels. A… CONTINUE READING
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