Cloning and characterization of a type II integral transmembrane protein gene, Itm2c, that is highly expressed in the mouse brain.

@article{Choi2001CloningAC,
  title={Cloning and characterization of a type II integral transmembrane protein gene, Itm2c, that is highly expressed in the mouse brain.},
  author={S C Choi and Jung-In Kim and Tae Hyung Kim and S Y Cho and Sung Sup Park and Kevin D. Kim and Sook Hwan Lee},
  journal={Molecules and cells},
  year={2001},
  volume={12 3},
  pages={391-7}
}
An Itm2C cDNA encoding a member of the mouse type II integral transmembrane protein (Itm2) was cloned from a mouse 13.5 days' post-coitum (dpc) embryonic head cDNA library. The nucleotide sequence and protein prediction analyses indicate that the membrane topology of the mouse Itm2c is a type II integral transmembrane protein with the N-terminus being intracellular and C-terminus, which is considered as either an extracellular or a luminal organelle domain. The predicted protein consists of 269… CONTINUE READING