Cloning and characterization of a novel endothelin receptor subtype in the avian class.

@article{Lecoin1998CloningAC,
  title={Cloning and characterization of a novel endothelin receptor subtype in the avian class.},
  author={L Lecoin and Takeshi Sakurai and Mai T. Ng{\^o} and Yoichiro Abe and Masashi Yanagisawa and Nicole M. Le Douarin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 6},
  pages={3024-9}
}
Endothelin 3 (EDN 3) and the endothelin receptor B (EDNRB) are involved in the development of neural crest and particularly of the melanocytes and the enteric nervous system. We reported previously that the avian EDNRB gene is expressed in the neural fold before crest cell migration and later on in all the neural crest derivatives except, at any developmental stage, in the melanocytic lineage. However, quail melanoblasts proliferate in response to EDN 3 stimulation in vitro. These observations… CONTINUE READING

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