Cloning and characterization of a novel Mg(2+)/H(+) exchanger.

  title={Cloning and characterization of a novel Mg(2+)/H(+) exchanger.},
  author={Orit Shaul and Donald W Hilgemann and J de-Almeida-Engler and Marc C E Van Montagu and D Inz and Gad Galili},
  journal={The EMBO journal},
  volume={18 14},
Cellular functions require adequate homeostasis of several divalent metal cations, including Mg(2+) and Zn(2+). Mg(2+), the most abundant free divalent cytoplasmic cation, is essential for many enzymatic reactions, while Zn(2+) is a structural constituent of various enzymes. Multicellular organisms have to balance not only the intake of Mg(2+) and Zn(2+), but also the distribution of these ions to various organs. To date, genes encoding Mg(2+) transport proteins have not been cloned from any… CONTINUE READING