Cloning and characterization of a gene for a 19 kDa fibrinogen-binding protein from Staphylococcus aureus.

@article{Bodn1994CloningAC,
  title={Cloning and characterization of a gene for a 19 kDa fibrinogen-binding protein from Staphylococcus aureus.},
  author={M K Bod{\'e}n and J. I. Flock},
  journal={Molecular microbiology},
  year={1994},
  volume={12 4},
  pages={599-606}
}
Staphylococcus aureus has been shown to interact specifically with fibrinogen. Three different extracellular fibrinogen-binding proteins, two of which have coagulase activity, are produced by S. aureus strain Newman. The role of these fibrinogen-binding proteins during staphylococcal colonization and infection has not yet been fully elucidated. Here we describe the cloning, sequencing and expression of a gene for a 19 kDa fibrinogen-binding protein. This gene, called fib, encodes a 165-amino… CONTINUE READING