Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac.

@article{Lee1996CloningAC,
  title={Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac.},
  author={Sojung Lee and Thomas T. Egelhoff and Amjad Mahasneh and Graham P. C{\^o}t{\'e}},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 43},
  pages={27044-8}
}
The motile activities of the small, single-headed class I myosins (myosin I) from the lower eukaryotes Acanthamoeba and Dictyostelium are activated by phosphorylation of a single serine or threonine residue in the head domain of the heavy chain. Recently, we purified a myosin I heavy chain kinase (MIHCK) from Dictyostelium based on its ability to activate… CONTINUE READING