Cloning and DNA sequence analysis of the cDNA for the common alpha-subunit of the ovine pituitary glycoprotein hormones.

@article{Bello1989CloningAD,
  title={Cloning and DNA sequence analysis of the cDNA for the common alpha-subunit of the ovine pituitary glycoprotein hormones.},
  author={Paul A Bello and Peter S. Mountford and Malcolm R. Brandon and Timothy E. Adams},
  journal={Nucleic acids research},
  year={1989},
  volume={17 24},
  pages={10494}
}
The a-subunit is common to the family of heterodimeric glycoprotein hormones FSH, LH, TSH and the placerual chorionic gonadotropin (CG). Clones coding for the pre a-subunit of the pituitary glycoprotein hormones were isolated from a lamb pituitary XgtlO cDNA library [1] using a synthetic oligonucleotide probe based on the published amino acid sequence of the ovine a-subunit [2] and nucleotide sequences for the bovine a-subunit [3,4]. The complete nucleotide sequence as determined by dideoxy… CONTINUE READING

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