Corpus ID: 49356111

Cloning and Characterization of cDNA Encoding the Porcine Mcl-1 Protein

  title={Cloning and Characterization of cDNA Encoding the Porcine Mcl-1 Protein},
  author={Jyh-Yih Chen and Wei-Tung Huang and Jen-Leih Wu},
  journal={Zoological Studies},
The cDNA sequence of the Mcl-1 protein was determined from a porcine model (Sus scrofa) and is compared to the corresponding genes of rat, human, and zebrafish. Multispecies comparison of the diversity of the Bcl-2 superfamily demonstrates Mcl-1 homology between the rat, human, and zebrafish. Porcine Mcl-1 cDNA has a size of 2487 nucleotides and encodes a polypeptide of 152 amino acids. Porcine Mcl-1 shares 83.9%, 85.3%, and 50.0% similarity to rat, human, and zebrafish Mcl-1, respectively… Expand

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