Cloning and Characterization of a Campylobacter jejuni Iron-Uptake Operon

@article{Galindo2001CloningAC,
  title={Cloning and Characterization of a Campylobacter jejuni Iron-Uptake Operon},
  author={Mario A Galindo and William A. Day and Brian H Raphael and Lynn A. Joens},
  journal={Current Microbiology},
  year={2001},
  volume={42},
  pages={139-143}
}
We report that C. jejuni modifies its outer membrane protein (OMP) repertoire when cultivated under iron-limiting conditions such as during incubation with epithelial cells. To identify genes encoding de novo expressed OMPs, a C. jejuni cosmid library was screened with antisera raised against proteins expressed in the presence of epithelial cells. A single clone was identified encoding an 80-kDa antigen. Sequence analysis of subclones identified an operon of three open reading frames (ORFs… CONTINUE READING
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