Cloning Adult Farm Animals: A Review of the Possibilities and Problems Associated with Somatic Cell Nuclear Transfer

@article{Edwards2003CloningAF,
  title={Cloning Adult Farm Animals: A Review of the Possibilities and Problems Associated with Somatic Cell Nuclear Transfer},
  author={J Lannett Edwards and F Neal Schrick and Malcolm D. Mccracken and Sarel R. van Amstel and Fred M. Hopkins and M. G. Welborn and Christopher J Davies},
  journal={American Journal of Reproductive Immunology},
  year={2003},
  volume={50}
}
In 1997, Wilmut et al. announced the birth of Dolly, the first ever clone of an adult animal. To date, adult sheep, goats, cattle, mice, pigs, cats and rabbits have been cloned using somatic cell nuclear transfer. The ultimate challenge of cloning procedures is to reprogram the somatic cell nucleus for development of the early embryo. The cell type of choice for reprogramming the somatic nucleus is an enucleated oocyte. Given that somatic cells are easily obtained from adult animals, cultured… 

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