• Biology, Medicine
  • Published in
    The Journal of biological…
    1990

Cloning, structural analysis, and expression of the human slow twitch skeletal muscle/cardiac troponin C gene.

@article{Schreier1990CloningSA,
  title={Cloning, structural analysis, and expression of the human slow twitch skeletal muscle/cardiac troponin C gene.},
  author={T. Schreier and Larry Kedes and R Gahlmann},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 34},
  pages={
          21247-53
        }
}
The two isoforms of troponin C that are differentially expressed in slow and fast twitch skeletal muscle are encoded by single copy genes. We are analyzing the mechanisms that control their highly restricted pattern of differential expression. The structure of the human fast twitch troponin C isoform gene has been reported (Gahlmann, R. and Kedes, L. (1990) J. Biol. Chem. 265, 12520-12528). Here we describe the isolation, nucleotide sequence, and localization of a regulating promoter element… CONTINUE READING

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hp://w w w .jb.org/ D ow nladed from T Schreier, L Kedes and R Gahlmann muscle/cardiac troponin C gene

F P., S. L. McKnight
  • Annu. Rev. Biochem. Natl. Acad. Sci
  • 1989