Cloning, sequencing and functional expression of a guinea pig lung bradykinin B2 receptor.

@article{Farmer1998CloningSA,
  title={Cloning, sequencing and functional expression of a guinea pig lung bradykinin B2 receptor.},
  author={Stephen G Farmer and Steven J. Powell and Deidre E Wilkins and Alexander Graham},
  journal={European journal of pharmacology},
  year={1998},
  volume={346 2-3},
  pages={291-8}
}
Kinin receptors are classified as B1 and B2 based upon agonist and antagonist potencies and cloning and expression studies. Using sequences from human and rat bradykinin B2 receptors, polymerase chain reaction (PCR) was utilized to isolate cDNA from guinea pig lung. The receptor obtained is predicted to have 372 amino acids and shares > 80% sequence… CONTINUE READING