Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans 1 The nucleotide sequences of human OGFr have been deposited in GenBank under accession numbers AF172449, AF172450, AF172451, AF172452, and AF172453. 1

@article{Zagon2000CloningSC,
  title={Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans
 1
 The nucleotide sequences of human OGFr have been deposited in GenBank under accession numbers AF172449, AF172450, AF172451, AF172452, and AF172453.
 
 
 1
 
},
  author={Ian S. Zagon and Michael F Verderame and Sandra S Allen and Patricia J. McLaughlin},
  journal={Brain Research},
  year={2000},
  volume={856},
  pages={75-83}
}
An opioid growth factor receptor (OGFR) for [Met5]-enkephalin in Chlamys farreri.
Regulation of cell proliferation by the opioid growth factor receptor is dependent on karyopherin β and Ran for nucleocytoplasmic trafficking
TLDR
The results indicate that the regulation of cell proliferation by the OGF–OGFr axis is dependent on nucleocytoplasmic transport by karyopherin β1 as well as the gradient of RanGTP/RanGDP across the nuclear envelope, but is not reliant on adaptor molecules related to kARYopherin α.
Prevention and delay in progression of human pancreatic cancer by stable overexpression of the opioid growth factor receptor.
TLDR
Data support OGFr gene function as a regulator of cell proliferation that impacts on tumorigenic expression, and suggest that molecular and pharmacological manipulation of OGFr may prevent or delay human pancreatic cancer.
Targeting the opioid growth factor: Opioid growth factor receptor axis for treatment of human ovarian cancer
TLDR
Preclinical data support the transition of these novel therapies for treatment of human ovarian cancer from the bench to bedside to provide additional targets for treatment for this devastating disease.
MUC1-like tandem repeat proteins are broadly immunogenic in cancer patients.
TLDR
Using sera from a long-term surviving metastatic melanoma patient vaccinated with irradiated, autologous tumor cells engineered to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), an antigen reported to be a putative opioid growth factor receptor (OGFr) was identified and antibody responses to OGFr and a synthetic peptide representing aPutative alternative reading frame product (OG Fr-ARF) were frequently found in cancer patients.
Androgen represses opioid growth factor receptor (OGFR) in human prostate cancer LNCaP cells and OGFR expression in human prostate cancer tissue.
TLDR
This is the first study showing OGFR and OGFRL1 are androgen repressed genes, and these results suggest a role for the opioid signaling axis in prostate cancer.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 55 REFERENCES
cDNA cloning and chromosomal assignment of the gene encoding endothelin 3.
TLDR
Observations that genes encoding endothelin-related peptides are expressed in a variety of human tissues suggest that these peptides may participate in complex vasoregulatory mechanisms.
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
TLDR
A random primed expression cDNA library was constructed from the RNA of NG 108-15 cells that encodes a 371-amino acid-residue protein presenting all the structural characteristics of receptors that interact with guanine nucleotide-binding proteins.
Molecular cloning of the alpha 3 chain of human type IX collagen: linkage of the gene COL9A3 to chromosome 20q13.3.
TLDR
The present study completes the structure of human type IX collagen, and linkage for COL9A3 completes the genomic mapping of cartilage collagen genes.
Opioid growth factor is present in human and mouse gastrointestinal tract and inhibits DNA synthesis.
TLDR
Results indicate that an endogenous opioid peptide (OGF) and its receptor (zeta) reside in gastrointestinal epithelium and play a role in cellular renewal processes in a tonically inhibitory, direct, and circadian rhythm-dependent fashion.
The opioid growth factor, [Met5]-enkephalin, and the zeta opioid receptor are present in human and mouse skin and tonically act to inhibit DNA synthesis in the epidermis.
TLDR
The suggestion that an endogenous opioid peptide and its receptor are present and govern cellular renewal processes in the skin in a direct manner, regulating DNA synthesis in a tonically inhibitory, circadian rhythm-dependent fashion is suggested.
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
  • K. Yasuda, K. Raynor, G. Bell
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1993
TLDR
RNA blotting studies and in situ hybridization histochemistry showed that kappa opioid receptor mRNA was expressed at high levels in brain in the neocortex, hippocampus, amygdala, medial habenula, hypothalamus, locus ceruleus, and parabrachial nucleus, suggesting that this receptor may play a role in arousal and regulation of autonomic and neuroendocrine functions.
...
1
2
3
4
5
...