Cloning, sequencing, and characterization of the SdeAB multidrug efflux pump of Serratia marcescens.

@article{Kumar2005CloningSA,
  title={Cloning, sequencing, and characterization of the SdeAB multidrug efflux pump of Serratia marcescens.},
  author={Ayush Kumar and Elizabeth A. Worobec},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 4},
  pages={1495-501}
}
Serratia marcescens is an important nosocomial agent known for causing various infections in immunocompromised individuals. Resistance of this organism to a broad spectrum of antibiotics makes the treatment of infections very difficult. This study was undertaken to identify multidrug resistance efflux pumps in S. marcescens. Three mutant strains of S. marcescens were isolated in vitro by the serial passaging of a wild-type strain in culture medium supplemented with ciprofloxacin, norfloxacin… CONTINUE READING
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