Cloning, localization, and axonemal function of Tetrahymena centrin.

@article{Guerra2003CloningLA,
  title={Cloning, localization, and axonemal function of Tetrahymena centrin.},
  author={Charles W Guerra and Yuuko Wada and Vagn Leick and Aaron J. Bell and Peter Satir},
  journal={Molecular biology of the cell},
  year={2003},
  volume={14 1},
  pages={
          251-61
        }
}
Centrin, an EF hand Ca(2+) binding protein, has been cloned in Tetrahymena thermophila. It is a 167 amino acid protein of 19.4 kDa with a unique N-terminal region, coded by a single gene containing an 85-base pair intron. It has > 80% homology to other centrins and high homology to Tetrahymena EF hand proteins calmodulin, TCBP23, and TCBP25. Specific cellular localizations of the closely related Tetrahymena EF hand proteins are different from centrin. Centrin is localized to basal bodies… CONTINUE READING