Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms.

@article{Nash1998CloningGS,
  title={Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms.},
  author={Scott Nash and Bruno Giros and Stephen F Kingsmore and Kyoung Mi Kim and S el-Mestikawy and Qian Dong and Francesca Fumagalli and Michael F. Seldin and Marc G. Caron},
  journal={Receptors & channels},
  year={1998},
  volume={6 2},
  pages={113-28}
}
Two genes were identified and characterized that express cDNAs related to previously identified neurotransmitter and/or osmolyte transporters, but which are expressed specifically in the kidney. RNA transcribed from one of these two genes (XT2) was found to undergo an extensive degree of alternative splicing to generate six distinct isoforms. The intron-exon structure of the XT2 gene and the sites of alternative splicing were identified. Expression of the second gene (XT3) was found to be… CONTINUE READING

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RNA transcribed from one of these two genes ( XT2 ) was found to undergo an extensive degree of alternative splicing to generate six distinct isoforms .
RNA transcribed from one of these two genes ( XT2 ) was found to undergo an extensive degree of alternative splicing to generate six distinct isoforms .
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