Cloning, functional expression and primary characterization of Vibrio parahaemolyticus K+/H+ antiporter genes in Escherichia coli.

@article{Radchenko2006CloningFE,
  title={Cloning, functional expression and primary characterization of Vibrio parahaemolyticus K+/H+ antiporter genes in Escherichia coli.},
  author={Martha V. Radchenko and Rungaroon Waditee and Sawako Oshimi and Masahiro Fukuhara and Teruhiro Takabe and Tatsunosuke Nakamura},
  journal={Molecular microbiology},
  year={2006},
  volume={59 2},
  pages={
          651-63
        }
}
The regulation of internal Na(+) and K(+) concentrations is important for bacterial cells, which, in the absence of Na(+) extrusion systems, cannot grow in the presence of high external Na(+). Likewise, bacteria require K(+) uptake systems when the external K(+) concentration becomes too low to support growth. At present, we have little knowledge of K(+) toxicity and bacterial outward-directed K(+) transport systems. We report here that high external concentrations of K(+) at alkaline pH are… CONTINUE READING
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