Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c.

@article{Weinberg1994CloningEA,
  title={Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c.},
  author={David H. Weinberg and Piyush Trivedi and Carina P. Tan and Sankar A Mitra and A Perkins-Barrow and D Borkowski and Catherine D. Strader and Marvin Bayne},
  journal={Biochemical and biophysical research communications},
  year={1994},
  volume={201 3},
  pages={1296-304}
}
The three human alpha adrenergic receptor subtypes, alpha 1a, alpha 1b, and alpha 1c, have been cloned, expressed in COS-7 cells, and characterized pharmacologically. Competition binding studies of several adrenergic ligands with the three human receptor subtypes reveals a distinct pharmacological profile for each receptor subtype. RNase protection analysis… CONTINUE READING