Cloning, characterization, localization, and mutational screening of the human BARX1 gene.

@article{Gould2000CloningCL,
  title={Cloning, characterization, localization, and mutational screening of the human BARX1 gene.},
  author={D. Gould and M. Walter},
  journal={Genomics},
  year={2000},
  volume={68 3},
  pages={
          336-42
        }
}
  • D. Gould, M. Walter
  • Published 2000
  • Biology, Medicine
  • Genomics
  • The Bar subclass of homeodomain proteins was first identified for its role in Drosophila eye development. The Bar subclass homolog, Barx1, has since been cloned in mouse and in chick. The expression of Barx1 in developing teeth and craniofacial mesenchyme of neural crest origin makes it a strong candidate for the related human disorders of Axenfeld-Reiger syndrome (ARS) and iridogoniodysgenesis syndrome (IGDS). Here we report the cloning and characterization of a novel human Bar class gene… CONTINUE READING
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