Cloning, characterization, and expression of a G-protein-coupled receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide, PSFHSWSamide, as its endogenous ligand.

@article{Cox1997CloningCA,
  title={Cloning, characterization, and expression of a G-protein-coupled receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide, PSFHSWSamide, as its endogenous ligand.},
  author={K J Cox and Cornelis P. Tensen and Roel C. van der Schors and Ka Wan Li and Harm van Heerikhuizen and E. Vreugdenhil and Wijnand P. M. Geraerts and J. F. Burke},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1997},
  volume={17 4},
  pages={1197-205}
}
Neuropeptides are known to be important signaling molecules in several neural systems of the pond snail Lymnaea stagnalis. Although the functions of these peptides have been studied in many neurons, the nature of the postsynaptic signal transduction is mainly unknown. The cloning and characterization of neuropeptide receptors in Lymnaea thus would be very valuable in further elucidating peptidergic pathways. Indirect evidence suggests that these neuropeptides operate via G-protein-coupled… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 40 references

The diuretic activity of a series of cephalomyotropic neuropeptides, the achetakinins, on isolated Malpighian tubules of the house cricket, Acheta domesticus

GM Coast, GM Holman, RJ Nachman
J Insect Physiol • 1990
View 6 Excerpts
Highly Influenced

The isolation and identification of 3 diuretic kinins from the abdominal ventral nerve cord of adult Helicoverpa zea

MB Blackburn, RM Wagner, +3 authors AK Raina
J Insect Physiol 41:723–730 • 1996
View 2 Excerpts

1994b) A G protein-coupled receptor with low density lipoprotein motifs suggests a role for lipoproteins in G-linked signal transduction

CP Tensen, ER van Kesteren, +4 authors E Vreugdenhil
1994
View 3 Excerpts

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