Clonidine potentiates drug induced self-injurious behavior in rats
@article{Mueller1983ClonidinePD, title={Clonidine potentiates drug induced self-injurious behavior in rats}, author={K. Mueller and W. Nyhan}, journal={Pharmacology Biochemistry and Behavior}, year={1983}, volume={18}, pages={891-894} }
Caffeine and amphetamine have been regarded as dramatically dissimilar drugs, both structurally and behaviorally. However, both are stimulants and (under certain conditions) both produce self-injurious behavior in rats which is potentiated by clonidine. Rats were pretreated with various doses of clonidine prior to daily administration of caffeine. In another experiment, rats which had been implanted with continuous release amphetamine pellets were injected twice daily with various doses of… CONTINUE READING
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References
SHOWING 1-10 OF 18 REFERENCES
Self-injurious behavior produced in rats by daily caffeine and continuous amphetamine
- Medicine
- Pharmacology Biochemistry and Behavior
- 1982
- 63
Modulation of the behavioral effects of amphetamine in rats by clonidine.
- Medicine
- European journal of pharmacology
- 1982
- 10
Pharmacologic control of pemoline induced self-injurious behavior in rats
- Psychology, Medicine
- Pharmacology Biochemistry and Behavior
- 1982
- 61
Chronic methylxanthine treatment in rats: A comparison of Wistar and Fischer 344 strains
- Medicine
- Pharmacology Biochemistry and Behavior
- 1981
- 17
Possible involvement of a central noradrenergic system in automutilation induced by clonidine in mice.
- Medicine
- Japanese journal of pharmacology
- 1977
- 22
- PDF
Behavioral and neurochemical effects of caffeine in normal and aggressive mice.
- Psychology, Medicine
- Pharmacology, biochemistry, and behavior
- 1973
- 29
Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine
- Chemistry, Medicine
- Brain Research
- 1975
- 882
A slow-release silicone pellet for chronic amphetamine administration.
- Chemistry, Medicine
- European journal of pharmacology
- 1977
- 41
Automutilation induced by clonidine in mice.
- Psychology, Medicine
- European journal of pharmacology
- 1975
- 36
Release of norepinephrine in the central nervous system by theophylline and caffeine.
- Chemistry, Medicine
- European journal of pharmacology
- 1970
- 199