Clonidine inhibits and phorbol acetate activates glutamate release from rat spinal synaptoneurosomes.

@article{Shinomura1999ClonidineIA,
  title={Clonidine inhibits and phorbol acetate activates glutamate release from rat spinal synaptoneurosomes.},
  author={Tetsutaro Shinomura and Shinichi Nakao and Takehiko Adachi and Koh Shingu},
  journal={Anesthesia and analgesia},
  year={1999},
  volume={88 6},
  pages={1401-5}
}
UNLABELLED Glutamate is a major neural transmitter of noxious stimulation in the spinal cord. We measured glutamate release from rat spinal synaptoneurosomes by using an enzyme-linked fluorimetric assay. Glutamate was released from spinal cord synaptoneurosomes in response to the addition of 30 mM potassium chloride, 1 mM 4-aminopyridine, or 1 microM ionomycin in the presence of external calcium. There was less release of glutamate in the absence, versus the presence, of external calcium… CONTINUE READING
6 Citations
25 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…