Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials.

@article{Ppping2009ClonidineAA,
  title={Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials.},
  author={Daniel Matthias P{\"o}pping and Nadia Elia and Emmanuel Marret and Manuel Wenk and Martin R. Tram{\`e}r},
  journal={Anesthesiology},
  year={2009},
  volume={111 2},
  pages={406-15}
}
The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. The authors searched for randomized placebo-controlled trials testing the impact of adding clonidine to local anesthetics for peripheral single-injection nerve or plexus blocks in adults undergoing any surgery (except eye) without general anesthesia. Twenty trials (1,054 patients, 573 received clonidine) published 1992-2006 tested plexus (14 brachial, 1 cervical) and nerve blocks (2 sciatic/femoral… CONTINUE READING
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