Clonidine Improves Hyperarousal in Borderline Personality Disorder With or Without Comorbid Posttraumatic Stress Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial

@article{Ziegenhorn2009ClonidineIH,
  title={Clonidine Improves Hyperarousal in Borderline Personality Disorder With or Without Comorbid Posttraumatic Stress Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial},
  author={A. Ziegenhorn and S. Roepke and N. Schommer and A. Merkl and H. Danker-Hopfe and F. Perschel and I. Heuser and I. Anghelescu and C. Lammers},
  journal={Journal of Clinical Psychopharmacology},
  year={2009},
  volume={29},
  pages={170-173}
}
The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition borderline personality disorder (BPD) seems to constitute a very heterogeneous category. Therefore, pharmacological therapy is symptom-oriented or targets comorbid conditions. A high comorbidity exists between BPD and posttraumatic stress disorder (PTSD). In a double-blind, randomized, placebo-controlled crossover study, we sought to determine whether the antinoradrenergic agent clonidine was effective in reducing… Expand
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