Clonidine: clinical pharmacology and therapeutic use in pain management.

@article{Neil2011ClonidineCP,
  title={Clonidine: clinical pharmacology and therapeutic use in pain management.},
  author={M. Neil},
  journal={Current clinical pharmacology},
  year={2011},
  volume={6 4},
  pages={
          280-7
        }
}
  • M. Neil
  • Published 2011
  • Medicine
  • Current clinical pharmacology
Pain is an unpleasant sensory perception warning of actual or impending tissue damage. Pain serves a vital physiological role, however, severe and uncontrolled pain in the peri-operative setting can adversely affect outcome from surgery and lead to chronic pain. Multiple neurochemical and receptor processes are involved in pain perception but the role of pro-inflammatory cytokines and adrenergic pathways has only recently been recognised. Clonidine is an agonist at the alpha2-adrenergic… Expand
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