Cloned yeast and mammalian transcription factor TFIID gene products support basal but not activated metallothionein gene transcription.


Transcription factor IID (TFIID), the "TATA binding factor," is thought to play a key role in the regulation of eukaryotic transcriptional initiation. We have studied the role of TFIID in the transcription of the yeast metallothionein gene, which is regulated by the copper-dependent activator protein ACE1. Both basal and induced transcription of the… (More)


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