Cloned pigs produced by nuclear transfer from adult somatic cells

  title={Cloned pigs produced by nuclear transfer from adult somatic cells},
  author={Irina A. Polejaeva and S Chen and Todd D. Vaught and Raymond L. Page and James Mullins and Suyapa F Ball and Yifan Dai and Jeremy T. Boone and Shawn Austin Walker and David L. Ayares and Alan Colman and Keith H. S. Campbell},
Since the first report of live mammals produced by nuclear transfer from a cultured differentiated cell population in 1995 (ref. 1), successful development has been obtained in sheep, cattle, mice and goats using a variety of somatic cell types as nuclear donors. The methodology used for embryo reconstruction in each of these species is essentially similar: diploid donor nuclei have been transplanted into enucleated MII oocytes that are activated on, or after transfer. In sheep and goat pre… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 656 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 348 extracted citations

Review of somatic cell nuclear transfer in pig

View 14 Excerpts
Highly Influenced

Advances in swine in vitro embryo production technologies.

Reproduction in domestic animals = Zuchthygiene • 2010
View 4 Excerpts
Highly Influenced

Development of cloned embryos from porcine neural stem cells and amniotic fluid-derived stem cells.

Animal : an international journal of animal bioscience • 2010
View 4 Excerpts
Highly Influenced

656 Citations

Citations per Year
Semantic Scholar estimates that this publication has 656 citations based on the available data.

See our FAQ for additional information.