Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels.

@article{Smith1998ClonedHA,
  title={Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels.},
  author={Kelli E. Smith and Mary W. Walker and R P Artymyshyn and Jonathan A. Bard and Beth Borowsky and Joseph A. Tamm and Wei Yao and Pierrre J.-J. Vaysse and Theresa A. Branchek and Christophe Gerald and Keith A. Jones},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 36},
  pages={23321-6}
}
The neuropeptide galanin has been implicated in the regulation of processes such as nociception, cognition, feeding behavior, and hormone secretion. Multiple galanin receptors are predicted to mediate its effects, but only two functionally coupled receptors have been reported. We now report the cloning of a third galanin receptor distinct from GALR1 and GALR2. The receptor, termed GALR3, was isolated from a rat hypothalamus cDNA library by both expression and homology cloning approaches. The… CONTINUE READING
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Galanin GALR3 Receptors Activate K1 Channels

K. Kask, U. Langel, T. Bartfai
Cell. Mol. Neurobiol. 15, • 1995
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