Clonazepam as an augmenting agent in the treatment of childhood-onset obsessive-compulsive disorder.

@article{Leonard1994ClonazepamAA,
  title={Clonazepam as an augmenting agent in the treatment of childhood-onset obsessive-compulsive disorder.},
  author={Henrietta L. Leonard and Deborah Topol and Oscar Bukstein and D J Hindmarsh and Anita J Allen and Susan E. Swedo},
  journal={Journal of the American Academy of Child and Adolescent Psychiatry},
  year={1994},
  volume={33 6},
  pages={792-4}
}
This case study is of a young man with childhood onset of severe obsessive-compulsive disorder (OCD). The patient had no clinical improvement during therapeutic trials of clomipramine, fluoxetine, and fluvoxamine, including buspirone augmentation. The patient consumed 50 tablets of fluoxetine in a suicide attempt and experienced a total remission of his OCD symptoms for the first time in his life. This remission lasted approximately 1 month and raises interesting questions about the mechanism… CONTINUE READING

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