Clonally Related GABAergic Interneurons Do Not Randomly Disperse but Frequently Form Local Clusters in the Forebrain

@article{Sultan2016ClonallyRG,
  title={Clonally Related GABAergic Interneurons Do Not Randomly Disperse but Frequently Form Local Clusters in the Forebrain},
  author={Khadeejah T. Sultan and Zhi Han and Xin-Jun Zhang and Anjin Xianyu and Zhizhong Li and Kun Huang and Song-Hai Shi},
  journal={Neuron},
  year={2016},
  volume={92},
  pages={31-44}
}
Progenitor cells in the medial ganglionic eminence (MGE) and preoptic area (PoA) give rise to GABAergic inhibitory interneurons that are distributed in the forebrain, largely in the cortex, hippocampus, and striatum. Two previous studies suggest that clonally related interneurons originating from individual MGE/PoA progenitors frequently form local clusters in the cortex. However, Mayer et al. and Harwell et al. recently argued that MGE/PoA-derived interneuron clones disperse widely and… CONTINUE READING
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Clonally related interneurons are not constrained by functional or anatomical boundaries

  • C. Mayer, R. C. Bandler, G. Fishell
  • Neuron 92,
  • 2016
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