Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy.

  title={Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy.},
  author={Arne Warth and Stephan Macher-Goeppinger and Thomas Muley and Michael Thomas and Hans Hoffmann and Philipp Albert Schnabel and Roland Penzel and Peter Schirmacher and Sebastian Aulmann},
  journal={The European respiratory journal},
  volume={39 6},
Nonsmall cell lung cancers (NSCLCs) display a variety of morphological and molecular features. Accurate subtyping of NSCLC has been shown to predict patient survival as well as response rates and toxicities of specific drugs. Assessment of multifocal lung tumours and the distinction of synchronous primary tumours from intrapulmonary metastases represent an important problem as this decision significantly influences tumour staging and subsequent treatment strategies. In order to provide a basis… CONTINUE READING
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