Clonality and HPV infection analysis of concurrent glandular and squamous lesions and adenosquamous carcinomas of the uterine cervix.

@article{Ueda2008ClonalityAH,
  title={Clonality and HPV infection analysis of concurrent glandular and squamous lesions and adenosquamous carcinomas of the uterine cervix.},
  author={Yutaka Ueda and Takashi Miyatake and Mika Okazawa and Toshihiro Kimura and Takahito Miyake and Kazuko Fujiwara and Kiyoshi Yoshino and Ryuichi Nakashima and Masami Fujita and Takayuki Enomoto},
  journal={American journal of clinical pathology},
  year={2008},
  volume={130 3},
  pages={389-400}
}
We analyzed the clonality and human papillomavirus (HPV) infection status of concurrent glandular and squamous lesions and adenosquamous carcinomas of the uterine cervix to clarify their histogenesis. The glandular and squamous components were clonally different from each other in 7 informative concurrent lesions. HPV was episomal in 2 polyclonal glandular dysplasias (GDs). HPV was in a mixed integrated-episomal form in a monoclonal GD, an adenocarcinoma in situ, and an adenocarcinoma. Both… CONTINUE READING