Clonal origin of non-medullary thyroid tumours assessed by non-random X-chromosome inactivation.

@article{Moniz2002ClonalOO,
  title={Clonal origin of non-medullary thyroid tumours assessed by non-random X-chromosome inactivation.},
  author={S{\'o}nia Moniz and Ana L Catarino and Ana Rita Marques and Branca M Cavaco and Lu{\'i}s Gonçalves Sobrinho and Valeriano Leite},
  journal={European journal of endocrinology},
  year={2002},
  volume={146 1},
  pages={
          27-33
        }
}
OBJECTIVE X-chromosome inactivation analysis was performed in order to assess the clonal origin of non-medullary thyroid tumours and to distinguish between multicentricity and multifocality in multiple papillary thyroid carcinoma (PTC). METHODS One hundred and thirteen tumour samples from 31 patients with isolated PTC, 16 patients with multinodular PTC, 14 patients with follicular thyroid adenoma (FTA) and 15 patients with follicular thyroid carcinoma (FTC) were collected. The corresponding… CONTINUE READING

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