Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA

Abstract

Intratumor heterogeneity may lead to sampling bias and may present major challenges to personalized medicine and biomarker development. Despite many studies investigating genetic heterogeneity, epigenetic intratumor heterogeneity of promoter hypermethylation has only rarely been examined in breast cancer. To examine clonal intratumor heterogeneity of… (More)
DOI: 10.1038/modpathol.2013.207

Topics

4 Figures and Tables

Cite this paper

@article{Moelans2014ClonalIH, title={Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA}, author={Cathy Beatrice Moelans and Jolien S. de Groot and Xiaojuan Pan and Elsken van der Wall and Paul J. van Diest}, journal={Modern Pathology}, year={2014}, volume={27}, pages={869-874} }