Clonal interference and Muller's ratchet in spatial habitats.

@article{Otwinowski2014ClonalIA,
  title={Clonal interference and Muller's ratchet in spatial habitats.},
  author={Jakub Otwinowski and Joachim H A Krug},
  journal={Physical biology},
  year={2014},
  volume={11 5},
  pages={
          056003
        }
}
Competition between independently arising beneficial mutations is enhanced in spatial populations due to the linear rather than exponential growth of clones. Recent theoretical studies have pointed out that the resulting fitness dynamics is analogous to a surface growth process, where new layers nucleate and spread stochastically, leading to the build up of scale-invariant roughness. This scenario differs qualitatively from the standard view of adaptation in that the speed of adaptation becomes… 

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