Clonal diversity in Giardia duodenalis isolates from Thailand: evidences for intragenic recombination and purifying selection at the beta giardin locus.

@article{Kosuwin2010ClonalDI,
  title={Clonal diversity in Giardia duodenalis isolates from Thailand: evidences for intragenic recombination and purifying selection at the beta giardin locus.},
  author={Rattiporn Kosuwin and Chaturong Putaporntip and Urassaya Pattanawong and Somchai Jongwutiwes},
  journal={Gene},
  year={2010},
  volume={449 1-2},
  pages={1-8}
}
The beta giardin locus of Giardia duodenalis encodes a structural component of ventral disc and exhibits sequence variation among isolates rendering it a useful marker for genotypic analysis. To determine the distribution of genotypes of G. duodenalis in Thailand and to explore the extent of sequence variation in this locus, we deployed the PCR-RFLP method and sequence analysis of recombinant subclones from 30 clinical isolates. In total, assemblage B was more prevalent than assemblage A… CONTINUE READING
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