Clonal divergence in Escherichia coli as a result of recombination, not mutation.

@article{Guttman1994ClonalDI,
  title={Clonal divergence in Escherichia coli as a result of recombination, not mutation.},
  author={David S. Guttman and Daniel E. Dykhuizen},
  journal={Science},
  year={1994},
  volume={266 5189},
  pages={1380-3}
}
Nucleotide sequence analysis was performed on 12 natural isolates of Escherichia coli in four loci located in close proximity on the chromosome. A comparison of gene genealogies indicated that three recombination events have occurred in a subset of the strains (ECOR group A) in the time since their divergence from a common ancestor, while during the same time, no mutational divergence has occurred. The common ancestor of this subset existed no more than 2400 years ago, and recombination was… CONTINUE READING

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