Clonal cytogenetic abnormalities in Hodgkin's disease.

  title={Clonal cytogenetic abnormalities in Hodgkin's disease.},
  author={Marc Ladanyi and Nasser Z. Parsa and Kenneth Offit and Mitchell Wachtel and Daniel A Filippa and Suresh C. Jhanwar},
  journal={Genes, chromosomes & cancer},
  volume={3 4},
Cytogenetic studies of Hodgkin's disease (HD), in contrast to those of non-Hodgkin's lymphoma (NHL), have been limited to small numbers of cases with infrequently recurring aberrations, underscoring the need for additional studies in establishing a coherent cytogenetic picture of HD. Over a 6 1/2-year period, we received 95 specimens of HD for cytogenetic analysis. Analyzable chromosome preparations were obtained in 70 cases, of which 57 (81%) showed only normal metaphases. In the remaining 13… CONTINUE READING
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