Clonal analysis of T cell unresponsiveness to alloantigens induced by neonatal injection of F1 spleen cells into parental mice.

Abstract

Alloantigen-specific T cell precursors present in spleen cell populations obtained from parental mice that were rendered tolerant by the neonatal injection of F1 spleen cells were quantitated by clonal analysis, i.e., limiting dilution techniques. The results demonstrate that the frequencies for cytolytic as well as TCGF-producing (helper) and MAF-producing… (More)

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@article{Feng1983ClonalAO, title={Clonal analysis of T cell unresponsiveness to alloantigens induced by neonatal injection of F1 spleen cells into parental mice.}, author={Hui-Min Feng and Andrew L. Glasebrook and Howard D Engers and Jacques Louis}, journal={Journal of immunology}, year={1983}, volume={131 5}, pages={2165-9} }