Clonal aging in Paramecium tetraurelia. II. Evidence of functional changes in the macronucleus with age

@article{Aufderheide1987ClonalAI,
  title={Clonal aging in Paramecium tetraurelia. II. Evidence of functional changes in the macronucleus with age},
  author={K. Aufderheide},
  journal={Mechanisms of Ageing and Development},
  year={1987},
  volume={37},
  pages={265-279}
}
  • K. Aufderheide
  • Published 1987
  • Biology, Medicine
  • Mechanisms of Ageing and Development
The contribution of the macronucleus of Paramecium tetraurelia to the long term proliferation potential of a cell line was tested using a nuclear transplantation protocol. Macronuclei from young or old wild-type cells were injected into genetically marked host cells of a standard clonal age. The subsequent proliferation to clonal death of successfully and stably transformed hybrids was compared to the proliferation of injected but untransformed lines (injection controls). Young macronuclear… Expand
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