Clonal Selection from First Principles

  title={Clonal Selection from First Principles},
  author={Chris McEwan and Emma Hart},
Clonal selection is the keystone of mainstream immunology and computational systems based on immunological principles. For the latter, clonal selection is often interpreted as an asexual variant of natural selection, and thus, tend to be variations on evolutionary strategies. Retro-fitting immunological sophistication and theoretical rigour onto such systems has proved to be unwieldy. In this paper we assert the primacy of competitive exclusion over selection and mutation; providing theoretical… 


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