Clomipramine in obsessive-compulsive disorder: clinical response and plasma levels.

@article{Mavissakalian1990ClomipramineIO,
  title={Clomipramine in obsessive-compulsive disorder: clinical response and plasma levels.},
  author={Matig R Mavissakalian and Barry Jones and Stephen Olson and James M. Perel},
  journal={Journal of clinical psychopharmacology},
  year={1990},
  volume={10 4},
  pages={261-8}
}
Two related data sets are presented that point to a specific pharmacological effect and support a predominantly serotonergic mediation of clomipramine's antiobsessional effect. A significant placebo versus clomipramine contrast from both the between- and within-group perspectives was found in 25 patients with moderate to severe obsessive-compulsive disorder… CONTINUE READING