Clomiphene prevents cancellous bone loss from tibia of ovariectomized rats.

@article{Jimenez1997ClomiphenePC,
  title={Clomiphene prevents cancellous bone loss from tibia of ovariectomized rats.},
  author={M. T. De Anta Jimenez and David E. Magee and Henry U. Bryant and Russell T. Turner},
  journal={Endocrinology},
  year={1997},
  volume={138 5},
  pages={1794-800}
}
Estrogen inhibits postmenopausal bone loss and decreases fracture risk. Unfortunately, estrogen replacement therapy has many undesirable side effects, the majority of which are due to stimulation of reproductive tissues. Tissue specific estrogen agonists provide a promising new alternative to natural estrogens for hormone replacement. Clomiphene (CLO) is a… CONTINUE READING