Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11.

  title={Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11.},
  author={Ichiro Abe and Kanji Okumoto and Shigehiko Tamura and Yukio Fujiki},
  journal={FEBS letters},
  volume={431 3},
We cloned a human PEX11 cDNA by expressed sequence tag homology search using yeast Candida boidinii PEX11, followed by screening of human liver cDNA library. PEX11 encoded a peroxisomal protein Pex11p comprising 247 amino acids, with two transmembrane segments and a dilysine motif at the C-terminus. Pex11p comigrated in SDS-PAGE with a 28-kDa peroxisomal integral membrane protein (PMP28) isolated from the liver of clofibrate-treated rats and was crossreactive to anti-PMP28 antibody, thereby… CONTINUE READING


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