Clocks do not tick in unison: isolation of Clock and vrille shed new light on the clockwork model of the sand fly Lutzomyia longipalpis

@inproceedings{Gesto2015ClocksDN,
  title={Clocks do not tick in unison: isolation of Clock and vrille shed new light on the clockwork model of the sand fly Lutzomyia longipalpis},
  author={João Silveira Moledo Gesto and Gustavo Bueno Rivas and M{\'a}rcio G Pavan and Antonio Carlos Alves Meireles-Filho and Paulo Roberto de Amoretty and Nataly Ara{\'u}jo de Souza and Rafaela Vieira Bruno and Alexandre Afr{\^a}nio Peixoto},
  booktitle={Parasites & Vectors},
  year={2015}
}
Behavior rhythms of insect vectors directly interfere with the dynamics of pathogen transmission to humans. The sand fly Lutzomyia longipalpis is the main vector of visceral leishmaniasis in America and concentrates its activity around dusk. Despite the accumulation of behavioral data, very little is known about the molecular bases of the clock mechanism in this species. This study aims to characterize, within an evolutionary perspective, two important circadian clock genes, Clock and vrille… CONTINUE READING
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